听力与言语-语言病理学

行为科学

医学伦理学

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  • Studies of linkage in populations. XIII. A unique cause of linkage disequilibrium in natural populations of Drosophila robusta.

    abstract::Natural populations of Drosophila robusta are polymorphic for chromosomal gene arrangements in most of its range, the deciduous forests of North America east of the Rocky Mountains. Many of the gene arrangements are the result of paracentric inversions on both arms of the metacentric second chromosome. They are freque...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1046/j.1365-2540.1998.00341.x

    authors: Levitan M,Etges WJ

    更新日期:1998-06-01 00:00:00

  • Genetic relationships within the genus Beta determined using both PCR-based marker and DNA sequencing techniques.

    abstract::The sequences of ITS1 of the internal transcribed spacer regions of nuclear ribosomal DNA from 11 species or subspecies in four sections of the genus Beta were compared. Phylogeny of these wild beet taxa was inferred from the sequence data using phenetic and phylogenetic analyses. Multiple accessions from the same 11 ...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1046/j.1365-2540.1998.00332.x

    authors: Shen Y,Ford-Lloyd BV,Newbury HJ

    更新日期:1998-05-01 00:00:00

  • Further investigation on the regression method of mapping quantitative trait loci.

    abstract::The simple regression method of mapping quantitative trait loci (QTL) is further investigated in comparison with the mixture model maximum likelihood method under high heritabilities, dominant and missing markers. No significant difference between the two methods is detected in terms of errors of parameter estimation ...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1046/j.1365-2540.1998.00307.x

    authors: Xu S

    更新日期:1998-03-01 00:00:00

  • Genetic variation at marker loci and in quantitative traits in natural populations of Arabidopsis thaliana.

    abstract::Genetic variation was studied in quantitative traits and molecular markers in six natural Scandinavian populations of Arabidopsis thaliana. Only two of the populations had several molecular marker haplotypes and significant between-family variance components in quantitative traits. There was no genetic variation in th...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1997.137

    authors: Kuittinen H,Mattila A,Savolainen O

    更新日期:1997-08-01 00:00:00

  • Randomly amplified polymorphic DNA (RAPD) analysis of Atlantic Coast striped bass.

    abstract::Atlantic Coast striped bass exhibit exceptionally low levels of genetic variation. The ability of the randomly amplified polymorphic DNA (RAPD) method to uncover genetic variation in this highly conserved species was investigated. Sufficient levels of variation were detected to allow a population genetic analysis of t...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1997.4

    authors: Bielawski JP,Pumo DE

    更新日期:1997-01-01 00:00:00

  • Mitochondrial DNA variation within P-type cytoplasmic male sterility of Plantago lanceolata L.

    abstract::MtDNA restriction fragment polymorphisms were found between cytoplasmic male-sterility types P and R of Plantago lanceolata with the homologous probe pPl311 and maize mtDNA fragments derived from the regions of atp1, cox1 and cox2. No mtDNA differences were observed between male- sterile and restored plants with the s...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/sj.hdy.6880780

    authors: Groenendijk CF,Sandbrink JM,Brederode JV,van Damme JM

    更新日期:1997-01-01 00:00:00

  • Evidence for intragenic recombination within a novel genetic marker that distinguishes mussels in the Mytilus edulis species complex.

    abstract::We have used the polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) techniques to design two genetic markers for blue mussels in the Mytilus edulis species complex. Both of these markers target the gene encoding the mussel polyphenolic adhesive protein. The first marker, Glu-5', is hig...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1996.187

    authors: Rawson PD,Joyner KL,Meetze K,Hilbish TJ

    更新日期:1996-12-01 00:00:00

  • Testing the unique amplification event and the worldwide migration hypothesis of insecticide resistance genes with sequence data.

    abstract::In the mosquito Culex pipiens, over-production of esterases is a common insecticide resistance mechanism. Different alleles at the esterase A and B loci are known to occur in natural populations, as shown by enzyme electrophoresis and RFLP studies on the esterase B locus. Here we analyse the variability of the esteras...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1996.181

    authors: Guillemaud T,Rooker S,Pasteur N,Raymond M

    更新日期:1996-11-01 00:00:00

  • On the presence of DNA polymerase alpha in human lymphocyte nuclei and chromosomes.

    abstract::Experiments were carried out to correlate the cytological localization of DNA polymerase alpha with the presence of its specific mRNA in human lymphocytes studied at different times after phytohaemagglutinin stimulation. Our data indicated that in resting cells it is not possible to detect DNA polymerase alpha protein...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1996.123

    authors: Ennas MG,Suzuki H,Menegazzi M,Carcereri A,Hanaoka F,Gremo F,Nieddu M,Mezzanotte R

    更新日期:1996-08-01 00:00:00

  • Population genetics with RAPD-PCR markers: the breeding structure of Aedes aegypti in Puerto Rico.

    abstract::RAPD-PCR polymorphisms at 57 presumptive loci were used to examine the breeding structure of the mosquito Aedes aegypti in Puerto Rico. Mosquitoes were sampled from 16 locations in six cities and samples were located in a nested spatial design to examine local patterns of gene flow. Allele frequencies were estimated a...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1996.50

    authors: Apostol BL,Black WC 4th,Reiter P,Miller BR

    更新日期:1996-04-01 00:00:00

  • The genetic basis of murine and human sex determination: a review.

    abstract::Determination of mammalian sex depends on the presence or absence of a functional testis. Testes are determined by the activity of the testis determining factor encoded by the sex determining gene, Y (SRY) located on the Y chromosome. Considerable evidence suggests that the SRY gene is the only gene on the Y chromosom...

    journal_title:Heredity

    pub_type: 杂志文章,评审

    doi:10.1038/hdy.1995.179

    authors: McElreavey K,Barbaux S,Ion A,Fellous M

    更新日期:1995-12-01 00:00:00

  • Evolution of the rDNA spacer, ITS 2, in the ticks Ixodes scapularis and I. pacificus (Acari: Ixodidae).

    abstract::Evolution of the rDNA spacer, ITS 2, is examined by comparing 17 DNA sequences of the ticks, Ixodes scapularis and I. pacificus. The distribution of fixed interspecific differences and the relative frequency of base changes vs. insertions/deletions (indels) matches the distribution and relative frequency for intraspec...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1995.139

    authors: McLain DK,Wesson DM,Collins FH,Oliver JH Jr

    更新日期:1995-09-01 00:00:00

  • Ethanol tolerance and variation at the alcohol dehydrogenase (Adh) locus of Drosophila mauritiana.

    abstract::Drosophila mauritiana larvae are tolerant to ethanol as a supplementary nutritional resource at low concentrations. Higher levels of ethanol (5 per cent) in the food adversely affect larval behaviour causing reduced rates of locomotion and feeding which are associated with low larva-to-adult survival. Two codominant a...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1995.61

    authors: Muhammad-Ali AZ,Burnet B

    更新日期:1995-04-01 00:00:00

  • The evolutionary history of Drosophila buzzatii. XXXII. Linkage disequilibrium between allozymes and chromosome inversions in two colonizing populations.

    abstract::Chromosome polymorphism in Drosophila buzzatii is under selection but the genes responsible for the effect of the inversions of fitness are unknown. On the other hand, there is evidence for selection on several allozyme loci but the presence of paracentric inversions on the second chromosome, where most of the polymor...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1995.27

    authors: Betrán E,Quezada-Díaz JE,Ruiz A,Santos M,Fontdevila A

    更新日期:1995-02-01 00:00:00

  • Evolution in heterogeneous environments: genetic variability within and across different grains in Tribolium castaneum.

    abstract::The course of adaptation to heterogeneous environments is influenced by the magnitude of genetic variation for ecologically important characters within each environment and the extent of genotype x environment interaction. Using the genetic correlation between the expression of characters in different environments as ...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1995.10

    authors: Via S,Conner J

    更新日期:1995-01-01 00:00:00

  • Inversion polymorphism and extra bristles in Indian natural populations of Drosophila ananassae: joint variation.

    abstract::Five Indian natural populations of Drosophila ananassae were analysed for chromosome inversions and the presence of individuals with extra scutellar bristles in the F1 progeny of isofemale lines initiated from naturally impregnated females. Three commonly occurring inversions were found in these populations with varyi...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1994.188

    authors: Das A,Mohanty S,Parida BB

    更新日期:1994-10-01 00:00:00

  • Postcopulatory, prezygotic isolation: intraspecific and interspecific sperm precedence in Tribolium spp., flour beetles.

    abstract::We investigated intraspecific and interspecific patterns of paternity in Tribolium castaneum, the flour beetle, by mating females either to pairs of conspecific males or to one conspecific and one heterospecific male of the closely related species, T. freemani. Females of both species store sperm in the spermatheca af...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1994.114

    authors: Robinson T,Johnson NA,Wade MJ

    更新日期:1994-08-01 00:00:00

  • Sex-linkage of two enzyme loci in Oncorhyncus mykiss (rainbow trout)

    abstract::We report the first sex-linked loci in Oncorhynchus mykiss (rainbow trout). Previous cytological and breeding experiments have demonstrated an XX/XY sex determining system in this and other salmonid species. Joint segregation data from fathers indicated an average of 8.1 per cent recombination between HEX-2 and the se...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1994.67

    authors: Allendorf FW,Gellman WA,Thorgaard GH

    更新日期:1994-05-01 00:00:00

  • Increased recombination frequencies resulting from directional selection for geotaxis in Drosophila.

    abstract::Several classes of models have been suggested to explain how natural selection can favour non-zero recombination. Directional and fluctuating selection, abiotic and biotic, and selection against harmful mutations seem to be the most plausible factors, but little has been done to test the problem experimentally. Here w...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1994.7

    authors: Korol AB,Iliadi KG

    更新日期:1994-01-01 00:00:00

  • The effect of periodic bottlenecks on the competitive ability of Drosophila pseudoobscura lines.

    abstract::Competition experiments between several Drosophila pseudoobscura strains that were previously subjected to periodic bottlenecks of different sizes and D. willistoni have been carried out. Contrary to previous results with these two species, where stable coexistence was detected, populations of D. pseudoobscura displac...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1993.8

    authors: López Bueno JA,Moya A,González-Candelas F

    更新日期:1993-01-01 00:00:00

  • The alcohol dehydrogenase polymorphism in natural populations of Drosophila melanogaster: ADH activity variation restriction site polymorphism and the Adh cline.

    abstract::Alcohol dehydrogenase activity has been measured in 186 iso-second chromosome lines--104 from seven Australian populations and 82 from six Chinese populations. Restriction endonuclease variation in the Adh gene region in these lines has previously been described (Jiang & Gibson, 1991). The mean ADH activity of AdhF an...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1992.48

    authors: Jiang JC,Gibson JB

    更新日期:1992-04-01 00:00:00

  • The prospects for polymorphisms shared between species.

    abstract::Recent molecular evidence has shown that many MHC polymorphisms are not only shared between species but are in fact identical at the molecular level. Species that share these polymorphisms may be very distantly related and often diverged millions of generations ago. It is now known that this phenomenon is very unlikel...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1992.39

    authors: Golding B

    更新日期:1992-03-01 00:00:00

  • Developments in the meiotic analysis of hybrids. I. Review of theory and optimization in triploids.

    abstract::The theory, construction and optimization of a model of chromosome pairing in triploid hybrids are re-examined and the model reconstructed. A new approach to optimization is described that removes a bias in the estimation of x, the measure of relative affinity, by weighting the observed and calculated meiotic figure f...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1992.16

    authors: Chapman CGD,Kimber G

    更新日期:1992-02-01 00:00:00

  • On the developmental theory of ageing. II. The effect of developmental temperature on longevity in relation to adult body size in D. melanogaster.

    abstract::Flies from a wild type strain of Drosophila melanogaster, previously kept at 25 degrees C, were reared at either 20, 25 or 29 degrees C. As expected, developmental time and adult body size decreased with increasing temperature. Adult longevity of flies reared at 25 degrees C was slightly greater than that of flies rai...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:

    authors: Zwaan BJ,Bijlsma R,Hoekstra RF

    更新日期:1992-02-01 00:00:00

  • The alcohol dehydrogenase polymorphism in natural populations of Drosophila melanogaster: restriction map variation in the region of the Adh locus in populations from two hemispheres.

    abstract::Restriction endonuclease variation in the 12 kb region surrounding the Adh locus was measured in seven Australian and six Chinese populations of Drosophila melanogaster. There is a higher level of nucleotide-substitution variation in the Australian populations than in the Chinese, which is possibly a reflection of the...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1992.1

    authors: Jiang JC,Gibson JB

    更新日期:1992-01-01 00:00:00

  • A genetic analysis of reproductive barriers in Phacelia dubia.

    abstract::Investigations into the genetic basis of reproductive barriers among recognized and putative varieties in Phacelia dubia have provided evidence that even among closely related taxa, multiple pathways can lead to reproductive isolation. A nuclear-based reproductive barrier, expressed as partial hybrid sterility of both...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1991.97

    authors: Levy F

    更新日期:1991-12-01 00:00:00

  • Quantitative analysis of genetic differentiation among European and Chilean strains of Drosophila subobscura.

    abstract::An analysis of the interpopulational differences observed between four European and four Chilean stocks of Drosophila subobscura, with regard to wing size, egg-to-adult development time and preadult viability, shows highly significant differences between the eight stocks irrespective of the continent from which the fl...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1991.61

    authors: Budnik M,Cifuentes L,Brncic D

    更新日期:1991-08-01 00:00:00

  • Positional control of chiasma distribution in the house mouse. Chiasma distribution in mice homozygous and heterozygous for an inversion in chromosome 1.

    abstract::An examination of the chiasma distribution in chromosome 1 of male mice homozygous and heterozygous for a distal inversion In(1) 12Rk and in normal males was carried out. No differences in chiasma distribution were found between homozygotes for the inversion and homozygotes for normal chromosome 1. A significant decre...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1991.55

    authors: Gorlov IP,Ladygina T Yu,Serov OL,Borodin PM

    更新日期:1991-06-01 00:00:00

  • Allele frequency estimation at loci with incomplete co-dominant expression.

    abstract::Although allelic variants at a locus usually are expressed either dominantly or co-dominantly, there are many cases when a gene is dominantly expressed in some individuals and co-dominantly in others. We present a maximum-likelihood procedure for allele frequency estimation in such situations of "incomplete" co-domina...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1990.114

    authors: Jorde PE,Ryman N

    更新日期:1990-12-01 00:00:00

  • The origin of a double insertion of homogeneously staining regions in the house mouse (Mus musculus musculus).

    abstract::A high resolution analysis of the G-band patterns of normal and aberrant chromosomes 1, bearing two linked insertions of homogeneously staining regions (HSRs) in the house mouse (Mus musculus musculus) reveals the inverted pattern of the euchromatic region between the HSRs. On the basis of this analysis a hypothesis o...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1990.95

    authors: Agulnik SI,Borodin PM,Gorlov IP,Ladygina TYu,Pak SD

    更新日期:1990-10-01 00:00:00

  • Selection during a selfing programme. II. The effects of two or more rounds of selection.

    abstract::Theory presented in a previous paper has been used to provide a description of the responses expected from selection in two or more generations of a selfing series. Optimum two-stages and multi-stage selection programmes are described, for a limited set of circumstances, and compared with the single-stage designs desc...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1990.89

    authors: Cornish MA

    更新日期:1990-10-01 00:00:00

  • Inter- and intraspecific heterochromatin variation detected by restriction endonuclease digestion in two sibling species of the Anopheles maculipennis complex.

    abstract::The sibling species Anopheles atroparvus and Anopheles labranchiae are cytogenetically almost indistinguishable. The chromosome complement (2n = 6) consists of two pairs of autosomes and two heteromorphic sex chromosomes with largely homologous heterochromatic long arms. Treatment of chromosome preparations with the r...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1990.80

    authors: Marchi A,Mezzanotte R

    更新日期:1990-08-01 00:00:00

  • The biometrical genetics of competitive parameters in Drosophila melanogaster.

    abstract::Despite the importance of competition as an evolutionary determinant in natural populations there have been few studies of the genetical control of competitive ability. Here, we report the results of a biometrical analysis of four continuously varying traits which, between them, describe the competitive interactions i...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1990.27

    authors: Hemmat M,Eggleston P

    更新日期:1990-04-01 00:00:00

  • Allozyme polymorphism at the alpha Gpdh and Adh loci and fitness in Drosophila melanogaster.

    abstract::We have studied in Drosophila melanogaster the effects of allozyme variation at the alpha Gpdh and Adh loci on the following fitness components: female fecundity, egg hatchability, egg-to-adult survival under near-optimal and competitive conditions, rate of development under near-optimal and competitive conditions, an...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1989.108

    authors: Izquierdo JI,Rubio J

    更新日期:1989-12-01 00:00:00

  • Inversion polymorphisms in Trimerotropis pallidipennis (Orthoptera): clinical variation along an altitudinal gradient.

    abstract::Six populations of Trimerotropis pallidipennis located along an altitudinal gradient in the Antinaco-Los Colorados valley (La Rioja, Argentina), were cytologically analysed. The male karyotype consists of 23 chromosomes (22 + XO) with three long pairs submetacentric, the X-chromosome metacentric and the remaining ones...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1989.14

    authors: Confalonieri VA,Colombo PC

    更新日期:1989-02-01 00:00:00

  • The superimposition of heat-induced chiasma frequency changes in Locusta migratoria.

    abstract::Inbred laboratory stocks of the locust Locusta migratoria were used in two different types of experiment involving the superimposition of heat-induced changes in chiasma frequency. The first involved the administration of two heat-treatments at 40 degrees C alternating with a return to 30 degrees C. This was designed ...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1989.10

    authors: Henderson SA,Buss ME

    更新日期:1989-02-01 00:00:00

  • Variation in the amount and activity of esterase 6 in a natural population of Drosophila melanogaster.

    abstract::Forty-two homozygous lines each isoallelic for the Esterase 6 (Est-6) locus were extracted from a natural population of Drosophila melanogaster. Homogenates of 4-5 day old virgin adults of each sex from several replicate cultures of each line were assayed for EST6 activity. Depending on the line, males had from three ...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1989.4

    authors: Game AY,Oakeshott JG

    更新日期:1989-02-01 00:00:00

  • Low biochemical variability in European fallow deer (Dama dama L.): natural bottlenecks and the effects of domestication.

    abstract::Tissue and blood samples from 180 fallow deer (Dama dama L.) belonging to an Italian free-ranging population were studied for biochemical variability by means of cellulose acetate and polyacrylamide gel electrophoresis. The 51 putative genetic loci successfully resolved showed a very low level of variability (P = 0.02...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1988.131

    authors: Randi E,Apollonio M

    更新日期:1988-12-01 00:00:00

  • Diploid models of the handicap principle.

    abstract::"Fisherian" models of sexual selection by female choice assume that females prefer male characters which are initially advantageous or neutral; character and preference then spread through the population. Once female preference has evolved to a higher frequency, the male character can become more extreme and disadvant...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1988.44

    authors: Tomlinson IP

    更新日期:1988-04-01 00:00:00

  • Larval competition in Drosophila melanogaster. II. Comparing biological and competitive parameters.

    abstract::Recent developments in the analysis of density dependent competition in Drosophila melanogaster have identified two distinct parameters, namely the competitive pressure or aggression exerted by a genotype and the sensitivity or response of a genotype to such aggression. Assuming that response is more related to the ef...

    journal_title:Heredity

    pub_type: 杂志文章

    doi:10.1038/hdy.1988.34

    authors: de Miranda JR,Eggleston P

    更新日期:1988-04-01 00:00:00

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